Evidence for distinct histologic profile of nasal polyps with and without eosinophilia
نویسندگان
چکیده
منابع مشابه
Distinct characteristics of nasal polyps with and without eosinophilia.
INTRODUCTION Eosinophilic and noneosinophilic Nasal polyps (NPs) are different subtypes of NPs and require different treatment methods. OBJECTIVE To compare the histologic characteristics, mRNA and protein expression between Nasal Polyps with and without eosinophilia. METHODS NPs tissues were obtained from eighty-six NPs patients during surgery. Eosinophilic and noneosinophilic NPs were dis...
متن کاملT helper cell population and eosinophilia in nasal polyps.
OBJECTIVE To analyze the immunological pattern of nasal polyposis in patients with and without allergy, the percentages of CD4+ cells expressing intracellular interferon-gamma and interleukin-4 (T helper [T(H)] type 1 and 2 cells) were measured by flow cytometry in samples from patients with nasal polyps. METHODS Samples from 32 patients (16 atopic, 16 nonatopic) were studied. The fresh nasal...
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Background According to EPOS, chronic rhinosinusitis with and without nasal polyps diagnoses are defined by clinical criteria, supported with endoscopy. We want to know if it is possible to make an accurate distinction between patients with and without nasal polyps based on a limited number of clinical criteria, collected by health-related quality of life questionnaires. A validated instrument ...
متن کاملThe bacteriology of chronic rhinosinusitis with and without nasal polyps.
OBJECTIVE To compare the bacteriologic findings in ethmoidal biopsy specimens and nasal lavage samples from healthy control patients and from patients with chronic rhinosinusitis (CRS) with nasal polyps (CRSNP+) and without nasal polyps (CRSNP-). DESIGN Comparative microbiologic investigation. SETTING University hospital. PATIENTS The study included 31 CRSNP+ patients, 13 CRSNP- patients,...
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Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease that can be classified as eosinophilic or noneosinophilic. Nasal polyps can exhibit different types of mucosal inflammation and responses to treatment. Imbalanced ratios of T-helper 17(Th17) and regulatory T (Treg) cells may contribute to the pathogenesis of nasal polyps.This study assessed the frequency of Th17 and Tr...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 2011
ISSN: 0023-852X
DOI: 10.1002/lary.21969